Features

• 700 – 4000 cm⁻¹宽带可调谐
  
• 荧光干扰信号最低
  
• 高光谱分辨率高灵敏度
• 亚波长尺度空间分辨率
  
• F-CARS, E-CARS, P-CARS detection geometries
• Easy transformable to fluorescence, TPEF and SHG microscopes
• Up to 1300 μm excitation for TPEF
  Up to 1300 μm excitation for TPEF
   
• Specially designed cost-effective picosecond tunable laser system
  ● 用于活体细胞研究获得无光
  学漂白信号
  ● ● ● 系统集成 Ekspla 最新型
  PT259 激光器
  ● 系统可方便地转换成双光子
  激发荧光和倍频发生显微光
  谱仪
  

Applications

• Species selective spectroscopy and microscopy
• Multimodal nonlinear imaging
• Deep tissue in vivo imaging
• Long term live cell studies
• Non-destructive research for the biological and material sciences
• Your application is welcome…

Powerful and versatile tool for vibrational spectroscopy and chemically selective imaging:

• 免标记（Label-free）光学成像
  
• Minimally invasive technique
• Non-photobleaching signal
• 3D sample imaging capability
• NIR pump and Stokes wavelengths suitable for deep-tissue imaging
• Picosecond pulse duration – good compromise between efficiency and spectral resolution

      相干反斯托克斯拉曼光谱也称作相干反斯托克斯拉曼散射光谱(CARS) 是一种主要用于化学和物理及相关领域的光谱技术。和拉曼光谱类似其对于分子相同的振动能级特征，典型的是化学键的原子间振动，具有较高的检测灵敏度。和普通拉曼光谱学不同的之处在于，CARS 采用多个光子协同工作共同来检测分子的振动特性，因此其产生的信号光子之间彼此具有相关性。于是CARS信号强度通常比自发拉曼散射信号要高若干个量级。
      CARS 是一种涉及三路激光束的三阶非线性光学过程:
     一路频率为 ω _pump的泵浦光,一路频率为ω _Stokes 的斯托克斯光和一路频率为 ω _probe的探针光. 这些路激光和样品相互作用并产生一路相干光学信号，其频率处于反斯托克斯位置：
     ω _CARS = ω _pump - ω _Stokes  + ω _probe.
     当泵浦光 ω _pump 和斯托克斯光ω _Stokes 频率之差接近分子某个振动跃迁频率 ω _vib 时，CARS 信号ω _CARS会发生共振增强。
     Combining of coherent anti-Stokes Raman scattering (CARS) spectroscopy with the microscopy opens up unique method for chemical imaging. CARS microscopy permits vibrational imaging with high-sensitivity, high speed, and three-dimensional nearly diffraction limited spatial resolution.